ADAM8 affects glioblastoma progression by regulating osteopontin-mediated angiogenesis
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چکیده
منابع مشابه
KSHV-Mediated Angiogenesis in Tumor Progression
Human herpesvirus 8 (HHV-8), also known as Kaposi's sarcoma-associated herpesvirus (KSHV), is a malignant human oncovirus belonging to the gamma herpesvirus family. HHV-8 is closely linked to the pathogenesis of Kaposi's sarcoma (KS) and two other B-cell lymphoproliferative diseases: primary effusion lymphoma (PEL) and a plasmablastic variant of multicentric Castleman's disease (MCD). KS is an ...
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BACKGROUND The normal progression of the cell cycle requires sequential expression of cyclins. Rapid induction of cyclin D1 and its associated binding with cyclin-dependent kinases, in the presence or absence of mitogenic signals, often is considered a rate-limiting step during cell cycle progression through the G(1) phase. METHODOLOGY/PRINCIPAL FINDINGS In the present study, human umbilical ...
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More than 30 years ago, Judah Folkman hypothesized that tumor angiogenesis could be a target of anticancer therapy. Some of the initial studies were actually performed in patients with glioblastomas, which had the greatest extent of tumor angiogenesis among a variety of human malignancies. The identification of vascular endothelial growth factor (VEGF) also provided a firm foundation for the de...
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ژورنال
عنوان ژورنال: Biological Chemistry
سال: 2021
ISSN: 1437-4315,1431-6730
DOI: 10.1515/hsz-2020-0184